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Homepage – Forum Forums Newly Diagnosed With Bladder Cancer When Chemo Agent Is Used Post Turbt

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  • #8498
    Jack Moon
    Keymaster

    Many patients ask why or why not they have received an instillation of Mitomycin C right after their Turbt. Below is the recommendation from the CUA guidelines on management on Non-Muscle Invasive Bladder Cancer.
    Below is a summary:
    Chemotherapy
    Single immediate postoperative instillation
    • Immediate postoperative instillation of a chemotherapeutic
    agent is recommended for all patients with
    NMIBC after TURBT (Grade B recommendation).
    • The efficacy of the immediate postoperative instillation
    is optimal when administered within 6 hours from the
    time of TUR and significantly decreases if given beyond
    24 hours (Level of Evidence 2).
    • Patients with suspected bladder perforation or deep/
    extensive resection should not receive an immediate
    instillation (Grade C recommendation).
    • For patients in whom treatment with BCG is planned,
    the benefit of an immediate postoperative instillation of
    chemotherapy is less clear (Grade D recommendation)
    The entire guideline can be found at this link:

    https://www.cua.org/themes/web/assets/files/guidelines/en/3320.pdf

    All the best,
    Jack

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