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Hi, You are asking great questions! I will share my experience regarding muscle spasms. After my first TURBT with the associated treatment of mitomycin I did experience spasms at night. During the day I was uncomfortable, but ok. However, at night I would have spasms and pain that would get me out of bed – could not sleep. The occurrence of this was most severe 3 weeks after the treatment. It did settle down by week 5. Talk to your doctor about them – they can explain what is happening. My GP told me it was due to the nerves resting at night and being impacted by the mitomycin. Good luck with your BCG Treatments. As others have stated, you will experience discomfort and urgency to pee as the treatments progress. BCC is a great support! Dawn