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Hi Dawn. I had CIS back in 1992. I had one TURB and cystos every 3 months for 2 years and then every 6 for 2 years then yearly when it was discovered again 17 years later. Another TURB and tried BCG which made me so sick I would have discontinued it but I went with it for 8 weeks. then a 2nd opinion which found CIS again and an RC was advised. My uro decided to try Valstar and after about 2 years I have been clear. I think CIS is almost always high grade but mine is essentially stage 0 so I will keep having cystos. It it recurs we plan on another round of Valstar before going to an RC. As I understand it Valstar is not approved for use in Canada. I wish you well and will keep you in my prayers.